Cyclo-oxygenase-2 Inhibitors and Peripheral Thrombosis—A Case Report Demonstrating a Possible Adverse Effect
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چکیده
منابع مشابه
Evaluation of cytotoxicity mechanism of two cyclo-oxygenase-2 inhibitors in leukemia cell line
Introduction: Leukemia is considered one of the main causes of death, and current chemotherapeutic agents are unable to provide optimal responses due to chemo-resistance. Therefore, there is a constant need for new drugs. Cyclooxygenase- 2 (COX-2) inhibitors can be helpful by reducing the necessary dose of routine chemotherapeutic drugs. Herein, we evaluated the cytotoxicity activity as well...
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OBJECTIVES Non-Steroidal anti-inflammatory drugs (NSAIDS) have long been used as anti-inflammatory agents, yet their mode of action is not entirely clear. The inhibitory effects of NSAIDS on prostaglandin production can only partly explain their anti-inflammatory actions. This study was aimed at defining the role of cycl-oxygenase (COX) inhibitors on nitric oxide (NO) production in murine macro...
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This report confirms evidence that selective nonsteroidal anti-inflammatory drugs (NSAIDs), such as celecoxib, can lead to thrombotic cardiovascular events. Aspirin, a nonselective COX-1 (cyclo-oxygenase) and COX-2 inhibitor may result in gastric toxicity. For this reason, selective COX-2 inhibitors have been developed to reduce erosion of the gastric mucosa. Both selective and nonselective NSA...
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A 62-year-old man had been well until 10 years previously when he experienced a first attack of dry cough. Coughing continued and four years before admission, after a flu-like illness, attacks of breathlessness and wheezing began to occur. Though treated with bronchodilators and prednisone he noticed that asprin relieved his symptoms and began to take it regularly. The frequency and severity of...
متن کاملRole of the Selective Cyclo-oxygenase-2 (cox-2) Inhibitors in Children
Correspondence to: Mr Sean Turner, Clinical Services, Princess Margaret Hospital, Roberts Road, Perth, Western Australia 6008, Australia; sean.turner@health. wa.gov.au _________________________ T here has been a great deal written about the use of selective cyclo-oxygenase-2 (COX-2) inhibitors in the adult population. Yet despite this there is still controversy over their place in treatment and...
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ژورنال
عنوان ژورنال: European Journal of Vascular and Endovascular Surgery
سال: 2009
ISSN: 1078-5884
DOI: 10.1016/j.ejvs.2008.11.020